Output
Publications
Articles
Optimising diagnosis of resistant cytomegalovirus using next-generation sequencing
Jocelyn Hume, Nilanthy Vigneswaran, Kym Lowry, Emma L Sweeney, David M Whiley, Bradley J Gardiner
Pathology | 2026 Feb;58(1):105-107 | DOI: 10.1016/j.pathol.2025.09.006 | Epub 2025 Nov 13
Mediated Urgency: Exploring GBTQ+ Perceptions of Antibiotic-Resistant Sexually Transmitted Infections
Shiva Chandra, Alex Broom, Damien Ridge, Bridget Haire, Michelle Peterie, Catriona Bradshaw, Jennifer Broom, Lise Lafferty, Carla Treloar, Tanya Applegate, Rebecca Guy
Sociology of Health & Illness | 2026 Jan;48(1):e70137 | DOI: 10.1111/1467-9566.70137
Development and validation of a human 2D in vitro model of oral Neisseria gonorrhoeae infection
Syed Ameer Hamza, Rita Paolini, Caroline Moore, Magnus Unemo, Micheal McCullough, Jane S Hocking, Charlene Kahler, Antonio Celentano, Fabian Yuh Shiong Kong
Sexually Transmitted Infections | 2025 Dec 21:sextrans-2025-056603 | DOI: 10.1136/sextrans-2025-056603
In vitro evolution provides insights into mechanisms of Mycoplasma genitalium resistance to moxifloxacin
Teck-Phui Chua, Jose L Huaman, Jennifer Danielewski, Catriona S Bradshaw, Dorothy A Machalek, Michael J McDonald, Suzanne M Garland, Gerald L Murray
Journal of Antimicrobial Chemotherapy | 2025 Nov 4;80(11):2970-2977 | DOI: 10.1093/jac/dkaf324
Population-based concordance of Chlamydia trachomatis genotypes between ocular and urogenital samples in Nauru
Kym Lowry, Sue-Chen Apadinuwe, Mitchell Starr, Susan Star, Kathleen D Lynch, Anthony W Solomon, Philip Cunningham, Stephen Lambert, David Whiley, John Kaldor, Susana Vaz Nery
Microbiology Spectrum | 2025 Nov 4;13(11):e0320524 | DOI: 10.1128/spectrum.03205-24
Determining targets for ceftriaxone resistance detection in Neisseria gonorrhoeae based on genotype-phenotype data: an observational study
Sebastiaan J van Hal, Monica M Lahra, David M Whiley
The Lancet Microbe | 2025 Nov;6(11):101199 | DOI: 10.1016/j.lanmic.2025.101199 | Epub 2025 Oct 8
Emerging Dilemmas in the Age of Resistance: The Case of Sexually Transmitted Infections
Shiva Chandra, Alex Broom, Michelle Peterie, Damien Ridge, Katherine Kenny, Lise Lafferty, Carla Treloar, Tanya Applegate, Jennifer Broom
Qualitative Health Research | 2025 Nov;35(13):1437-1449 | DOI: 10.1177/10497323241302668
Sequencing of Mycoplasma genitalium genomes using a tiling amplicon method on the Nanopore MinION
Teck-Phui Chua, Jennifer Danielewski, Jose L Huaman, Erica L Plummer, Catriona S Bradshaw, Lenka A Vodstrcil, Dorothy A Machalek, Suzanne M Garland, Gerald L Murray
Letters in Applied Microbiology | 2025 Oct 3;78(10):ovaf119 | DOI: 10.1093/lambio/ovaf119
Selecting candidate Neisseria gonorrhoeae strains for oropharyngeal gonorrhoea human challenge: a genomics-based analysis of clinical isolates
Eloise Williams, Soo Jen Low, Georgina L Pollock, Mona L Taouk, Jacqueline Prestedge, Benjamin P Howden, Eric P F Chow, Christopher K Fairley, Kate L Seib, James S McCarthy, Shivani Pasricha, Deborah A Williamson
The Lancet Microbe | 2025 Sep;6(9):101105 | DOI: 10.1016/j.lanmic.2025.101105 | Epub 2025 Jul 10
GBTQ+ safe sex entanglements: Finding the bacterial in the age of resistant STIs and prevention innovation
Shiva Chandra, Alex Broom, Damien Ridge, Katherine Kenny, Michelle Peterie, Jennifer Broom, Bridget Haire Lise Lafferty, Carla Treloar, Stephanie Raymond, Catriona Bradshaw, Tanya Applegate, Rebecca Guy
Social Science & Medicine | 2025 Aug;379:118162 | DOI: 10.1016/j.socscimed.2025.118162
Tetracycline-resistant Neisseria gonorrhoeae global estimates—impacts on doxycycline post-exposure prophylaxis implementation and monitoring: a systematic review
Kim Do , Magnus Unemo , Chris Kenyon , Jane S Hocking , Fabian Yuh Shiong Kong
JAC-Antimicrobial Resistance | 2025 Jul 9;7(4):dlaf120 | DOI: 10.1093/jacamr/dlaf120
A novel azithromycin resistance mutation in Mycoplasma genitalium induced in vitro
Teck-Phui Chua, Jennifer Danielewski, Catriona S Bradshaw, Dorothy A Machalek, Suzanne M Garland, Jose L Huaman, Jørgen S Jensen, Gerald L Murray
Journal of Antimicrobial Chemotherapy | 2025 Jul 1;80(7):2044-2050 | DOI: 10.1093/jac/dkaf174
Evolving patterns of macrolide and fluoroquinolone resistance in Mycoplasma genitalium: an updated systematic review and meta-analysis
Teck-Phui Chua, Lenka A Vodstrcil, Gerald L Murray, Erica L Plummer, Jørgen S Jensen, Magnus Unemo, Eric P F Chow, Nicola Low, David M Whiley, Emma L Sweeney, Jane S Hocking, Jennifer A Danielewski, Suzanne M Garland, Christopher K Fairley, Lei Zhang, Catriona S Bradshaw, Dorothy A Machalek
The Lancet Microbe | 2025 Jul;6(7):101047 | DOI: 10.1016/j.lanmic.2024.101047 | Epub ahead of print
Factors that contribute to the success of primary isolation of Mycoplasma genitalium from clinical samples
Jose L Huaman, Catriona S Bradshaw, Teck-Phui Chua, Erica L Plummer, Jennifer A Danielewski, Lenka A Vodstrcil, Jorgen S Jensen, Suzanne M Garland, Natasha Wild, Gerald L Murray
Journal of Medical Microbiology | 2025 Jul;74(7):002040 | DOI: 10.1099/jmm.0.002040
Oral gepotidacin for the treatment of uncomplicated urogenital gonorrhoea (EAGLE-1): a phase 3 randomised, open-label, non-inferiority, multicentre study
Jonathan D C Ross, Janet Wilson, Kimberly A Workowski, Stephanie N Taylor, David A Lewis, Sally Gatsi, William Flight, Nicole E Scangarella-Oman, Charles Jakielaszek, Dan Lythgoe, Marcy Powell, Salim Janmohamed, Judith Absalon, Caroline Perry
The Lancet | 2025 May 3;405(10489):1608-1620 | DOI: 10.1016/S0140-6736(25)00628-2
CRISPR-Cas-b-Based Diagnostics for Point-of-Care Detection of Sexually Transmitted Infections: A Laboratory Development and Evaluation Study
Soo Jen Low, Matthew O’Neill, Janath A Fernando, William J Kerry, Jacqueline Prestedge, Natasha Wild, Simran Chahal, Georgina L Pollock, Georgina Papadakis, Marcelina Krysiak, Eloise Williams, Francesca Azzato, Thomas Tran, Christopher K Fairley, Chuan Kok Lim, Catriona Bradshaw, Marcus Y Chen, Deborah A Williamson, Shivani Pasricha
The Lancet Microbe | Available at SSRN: https://ssrn.com/abstract=5230642 | Preprint posted: 1 May 2025 | DOI: 10.2139/ssrn.5230642
Diversity of Mycoplasma genitalium strains in Australia: relationship with sexual networks and antimicrobial resistance
Teck-Phui Chua, Jennifer A Danielewski, Emma L Sweeney, Erica L Plummer, Catriona S Bradshaw, David M Whiley, Dorothy A Machalek, Suzanne M Garland, Gerald L Murray
European Journal of Clinical Microbiology & Infectious Diseases | 2025 May;44(5):1167-1175 | DOI: 10.1007/s10096-025-05081-0
GS-1 blocks entry of herpes viruses and more broadly inhibits enveloped viruses
E A Monson, M G Lloyd, R I Johnson, K Caracciolo, J Whan, T F Rau, S L Londrigan, J F Moffat, A J Mayfosh, K J Helbig
Antiviral Research | 2025 May;237:106136 | DOI: 10.1016/j.antiviral.2025.106136
Lefamulin for Mycoplasma genitalium treatment failure in Australia and the USA: a case series and pilot open-label parallel arm randomised trial
Meena S Ramchandani, Erica L Plummer, Anika Parker, Lenka A Vodstrcil, Olusegun O Soge, Ivette Aguirre, Joong Kim, James P Hughes, Lindley A Barbee, Jørgen Skov Jensen, Lisa E Manhart, Catriona S Bradshaw
Sexually Transmitted Infections | 2025 Mar 24;101(2):101-108 | DOI: 10.1136/sextrans-2024-056338
Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis
Lenka A Vodstrcil, Erica L Plummer, Christopher K Fairley, Jane S Hocking, Matthew G Law, Kathy Petoumenos, Deborah Bateson, Gerald L Murray, Basil Donovan, Eric P F Chow, Marcus Y Chen, John Kaldor, Catriona S Bradshaw; StepUp Team
The New England Journal of Medicine | 2025 March 6;392(10):947-957 | DOI: 10.1056/NEJMoa2405404
A Novel Ammonium Carboxylate Salt of Undecylenic Acid for the Topical Treatment of Gram-Positive and Antibiotic-Resistant Skin Infections
Alyce Mayfosh, Thomas Rau
Experimental Dermatology | 2025 Mar;34(3):e70075 | DOI: 10.1111/exd.70075
Trends in infections detected in women with cervicitis over a decade
Lenka A Vodstrcil, Erica L Plummer, Thuy Vy Nguyen, Christopher K Fairley, Eric P F Chow, Tiffany R Phillips, Catriona S Bradshaw
Frontiers in Reproductive Health | 2025 Feb 3;7:1539186 | DOI: 10.3389/frph.2025.1539186
PathoGD: an integrative genomics approach to primer and guide RNA design for CRISPR-based diagnostics
Soo Jen Low, Matthew O’Neill, William J Kerry, Natasha Wild, Marcelina Krysiak, Yi Nong, Francesca Azzato, Eileen Hor, Lewis Williams, George Taiaroa, Eike Steinig, Shivani Pasricha & Deborah A Williamson
Communications Biology | 2025 January 30;8(1):147 | DOI: 10.1038/s42003-025-07591-1
Antimicrobial Resistance in Curable Sexually Transmitted Infections
Lorenzo Giacani, Catriona S Bradshaw, Christina A Muzny, Keonte J Graves, Shivani Pasricha, Stephen J Jordan, Lao-Tzu Allan-Blitz
Current HIV/AIDS Reports | 2025 Jan 25;22(1):14 | DOI: 10.1007/s11904-025-00722-7
WHO global research priorities for antimicrobial resistance in human health
Silvia Bertagnolio, Zlatina Dobreva, Chad M Centner, Ioana Diana Olaru, Daniele Donà, Stefano Burzo, Benedikt D Huttner, Antoine Chaillon, Nebiat Gebreselassie, Teodora Wi, Mateusz Hasso-Agopsowicz, Benedetta Allegranzi, Hatim Sati, Verica Ivanovska, Kavita U Kothari, Hanan H Balkhy, Alessandro Cassini, Raph L Hamers, Kitty Van Weezenbeek; WHO Research Agenda for AMR in Human Health Collaborators
The Lancet Microbe | 2024 Nov;5(11):100902 | DOI: 10.1016/S2666-5247(24)00134-4
Longitudinal genomic analysis of Neisseria gonorrhoeae transmission dynamics in Australia
Mona L Taouk, George Taiaroa, Sebastian Duchene, Soo Jen Low, Charlie K Higgs, Darren Y J Lee, Shivani Pasricha, Nasra Higgins, Danielle J Ingle, Benjamin P Howden, Marcus Y Chen, Christopher K Fairley, Eric P F Chow & Deborah A Williamson
Nature Communications | 2024 September 14;15, Article number: 8076 (2024). | DOI: 10.1038/s41467-024-52343-0
Emergence of an extensively drug-resistant Neisseria gonorrhoeae clone
Sebastiaan J van Hal, Norelle Sherry, Geoff Coombs, Shakeel Mowlaboccus, David M Whiley, Monica M Lahra
The Lancet Infectious Diseases | 2024 August 7;24:00486-9. | DOI: 10.1016/S1473-3099(24)00486-9
A novel murine model mimicking male genital Neisseria species infection using Neisseria musculi
Emily R Bryan, Julia McRae, Vishnu Kumar, Logan K Trim, Toby I Maidment, Jacob A D Tickner, Emma L Sweeney, Elizabeth D Williams, David M Whiley, Kenneth W Beagley
Biology of Reproduction | 2024 July 8;ioae100. | DOI: 10.1093/biolre/ioae100
The AMR Hub: a public–private partnership to overcome barriers to commercialisation and deliver antimicrobial stewardship innovations
Michelle Bonello, Tanya L Applegate, Steve Badman, Catriona S Bradshaw, Alex Broom, Paul Field, Jane S Hocking, Wilhelmina M Huston, Fabian Kong, Gerald L Murray, Elisa Mokany, Shivani Pasricha, Alison V Todd, David M Whiley, Virginia Wiseman, and Rebecca Guy, on behalf of investigators and partner investigators of the AMR Hub
Microbiology Australia | 2024 May 23;45:48-53 | DOI: 10.1071/MA24017
Response to the ASHM 2023 statement on the use of doxy-PEP in Australia: considerations and recommendations
Sara F E Bell, Emma L Sweeney, Fabian Y S Kong, David M Whiley, Catriona S Bradshaw, Jacob A Tickner
The Medical Journal of Australia | 2024 Apr 15;220(7):356-360. | DOI: 10.5694/mja2.52255
STI pathogens in the oropharynx: update on screening and treatment
Eric P F Chow, Christopher K Fairley, Fabian Y S Kong
Current Opinion in Infectious Diseases | 2024 Feb 1;37(1):35-45 | DOI: 10.1097/QCO.0000000000000997
Concurrent parC and gyrA fluoroquinolone resistance mutations and associated strains in Mycoplasma genitalium in Queensland, Australia
Nicole G Ertl, Taylah K Anderson, Carolyn J Pardo, Toby I Maidment, Gerald L Murray, Catriona S Bradshaw, David M Whiley, Emma L Sweeney
Journal of Antimicrobial Chemotherapy | 2023 Dec 15:dkad373 | DOI: 10.1093/jac/dkad373
Sex, drugs and superbugs: The rise of drug resistant STIs
Alex Broom, Michelle Peterie, Damien Ridge, Lise Lafferty, Katherine Kenny, Jennifer Broom, Angela Kelly-Hanku, Carla Treloar, Tanya Applegate
SSM – Qualitative Research in Health | 2023 December;4:100310 | DOI: 10.1016/j.ssmqr.2023.100310
Evaluating preanalytical sample storage parameters for nucleic acid-based detection of Neisseria gonorrhoeae
Janath A Fernando, Marcelina Krysiak, Jacqueline Prestedge, Francesca Azzato, Deborah A Williamson, Shivani Pasricha
Sexually Transmitted Infections | 2023 Nov 24:sextrans-2023-055859 | DOI: 10.1136/sextrans-2023-055859
Efficacy of Sitafloxacin for Mycoplasma genitalium in an Era of Increasing Antimicrobial Resistance
Ranjit S Samra, Erica L Plummer, Lenka A Vodstrcil, Ivette Aguirre, Emily J Clarke, Christopher K Fairley, Eric P F Chow, Catriona S Bradshaw
Open Forum Infectious Diseases | 2023 Nov 22;10(12):ofad590 | DOI: 10.1093/ofid/ofad590
Economies of resistance
Michelle Peterie, Alex Broom, Katherine Kenny, Jennifer Broom, David Regan, Lise Lafferty, Angela Kelly-Hanku, Carla Treloar
Critical Public Health | Published online: 24 Oct 2023 | DOI: 10.1080/09581596.2023.2271140
Selection of Neisseria gonorrhoeae ceftriaxone resistance using doxycycline post-exposure prophylaxis
David M Whiley, Jacob A Tickner, Ratan L Kundu, Tiffany R Hogan, Sebastiaan J van Hal, Monica M Lahra
The Lancet Infectious Diseases | 2023 Aug;23(8):e268-e269 | DOI: 10.1016/S1473-3099(23)00359-6
Neisseria gonorrhoeae ciprofloxacin susceptibility testing and gyrA targets
Jacob A Tickner, Ella Trembizki, David M Whiley
The Lancet Microbe | 2023 Aug;4(8):e574 | DOI: 10.1016/S2666-5247(23)00149-0
Important considerations regarding the widespread use of doxycycline chemoprophylaxis against sexually transmitted infections
Fabian Y S Kong, Chris Kenyon, Magnus Unemo
Journal of Antimicrobial Chemotherapy | 2023 Jul 5;78(7):1561-1568 | DOI: 10.1093/jac/dkad129
Antimicrobial susceptibility assays for Neisseria gonorrhoeae: a proof-of-principle population-based retrospective analysis
Sara F E Bell, Robert S Ware, David A Lewis, Monica M Lahra, David M Whiley
The Lancet Microbe | 2023 Jul;4(7):e544-e551 | DOI: 10.1016/S2666-5247(23)00071-X
gyrA Mutations in Mycoplasma Genitalium and Their Contribution to Moxifloxacin Failure: Time for the Next Generation of Resistance-guided Therapy
Gerald L Murray, Erica L Plummer, Kaveesha Bodiyabadu, Lenka A Vodstrcil, Jose L Huaman, Jennifer A Danielewski, Teck Phui Chua, Dorothy A Machalek, Suzanne Garland, Michelle Doyle, Emma L Sweeney, David M Whiley, Catriona S Bradshaw
Clinical Infectious Diseases | 2023 Jun 16;76(12):2187-2195 | DOI: 10.1093/cid/ciad057
Quantitation of Mycoplasma genitalium using droplet digital PCR
Cheng Rui Peh, Jennifer Danielewski, Teck Phui Chua, Kaveesha Bodiyabadu, Dorothy A Machalek, Suzanne M Garland, Catriona S Bradshaw, Gerald L Murray
Letters in Applied Microbiology | 2023 Jun 1;76(6):ovad064 | DOI: 10.1093/lambio/ovad064
The Urethral Microbiota of Men with and without Idiopathic Urethritis
Erica L Plummer, Larissa K Ratten, Lenka A Vodstrcil, Gerald L Murray, Jennifer A Danielewski, Christopher K Fairley, Suzanne M Garland, Eric P F Chow, Catriona S Bradshaw
mBio | 2022 Oct 26;13(5):e0221322 | DOI: 10.1128/mbio.02213-22
Vulnerability and antimicrobial resistance
Alex Broom, Michelle Peterie, Katherine Kenny, Jennifer Broom, Angela Kelly-Hanku, Lise Lafferty, Carla Treloar, Tanya Applegate
Critical Public Health | 2022 Sep 22; 33(3):308-317 | DOI: 10.1080/09581596.2022.2123733
Combination therapy for Mycoplasma genitalium, and new insights into the utility of parC mutant detection to improve cure
Lenka A Vodstrcil, Erica L Plummer, Michelle Doyle, Gerald L Murray, Kaveesha Bodiyabadu, Jorgen S Jensen, David Whiley, Emma Sweeney, Deborah A Williamson, Eric P F Chow, Christopher K Fairley, Catriona S Bradshaw
Clinical Infectious Diseases | 2022 Sep 14;75(5):813-823 | DOI: 10.1093/cid/ciab1058
Individualised treatment of Mycoplasma genitalium infection – it is time to incorporate quinolone resistance testing into clinical care
Emma L Sweeney, Catriona S Bradshaw, Gerald L Murray, David M Whiley
The Lancet Infectious Diseases | 2022 Sep;22(9):e267-e270 | DOI: 10.1016/S1473-3099(21)00629-0
Mycoplasma genitalium: enhanced management using expanded individualised treatment strategies, Sex
Emma L Sweeney, David M Whiley, Gerald L Murray, Catriona S Bradshaw
Sexual Health | 2022 Aug;19(4):248-254 | DOI: 10.1071/SH22012
Novel probe-based melting curve assays for the characterisation of fluoroquinolone resistance in Mycoplasma genitalium
Jacob A Tickner, Catriona S Bradshaw, Gerald L Murray, David M Whiley, Emma L Sweeney
Journal of Antimicrobial Chemotherapy | 2022 May 29;77(6):1592-1599 | DOI: 10.1093/jac/dkac097
parC variants in Mycoplasma genitalium: trends over time and association with moxifloxacin failure
★ Editor’s Pick
Gerald L Murray, Kaveesha Bodiyabadu, Lenka A Vodstrcil, Dorothy A Machalek, Jennifer Danielewski, Erica L Plummer, Suzanne M Garland, David M Whiley, Emma L Sweeney, Catriona S Bradshaw
Antimicrobial Agents in Chemotherapy | 2022 May 17;66(5):e0027822 | DOI: 10.1128/aac.00278-22
Impact of 16S rRNA Single Nucleotide Polymorphisms on Mycoplasma genitalium Organism Load with Doxycycline Treatment
Teck-Phui Chua, Jennifer Danielewski, Kaveesha Bodiyabadu, Catriona S Bradshaw, Dorothy A Machalek, Suzanne M Garland, Erica L Plummer, Lenka A Vodstrcil, Gerald L Murray
Antimicrobial Agents and Chemotherapy | 2022 May 17;66(5):e0024322 | DOI: 10.1128/aac.00243-22