Output

Publications

 

 

Articles

Development and validation of a human 2D in vitro model of oral Neisseria gonorrhoeae infection

Syed Ameer Hamza, Rita Paolini, Caroline Moore, Magnus Unemo, Micheal McCullough, Jane S Hocking3, Charlene Kahler, Antonio Celentano, Fabian Yuh Shiong Kong

Sexually Transmitted Infections | 2025 Oct 5:sextrans-2025-056603 | DOI: 10.1136/sextrans-2025-056603

Sequencing of Mycoplasma genitalium genomes using a tiling amplicon method on the Nanopore MinION

Teck-Phui Chua, Jennifer Danielewski, Jose L Huaman, Erica L Plummer, Catriona S Bradshaw, Lenka A Vodstrcil, Dorothy A Machalek, Suzanne M Garland, Gerald L Murray

Letters in Applied Microbiology | 2025 Sep 30:ovaf119 | DOI: 10.1093/lambio/ovaf119

In vitro evolution provides insights into mechanisms of Mycoplasma genitalium resistance to moxifloxacin

Teck-Phui Chua, Jose L Huaman, Jennifer Danielewski, Catriona S Bradshaw, Dorothy A Machalek, Michael J McDonald, Suzanne M Garland, Gerald L Murray

Journal of Antimicrobial Chemotherapy | 2025 Sep 16:dkaf324 | DOI: 10.1093/jac/dkaf324

Tetracycline-resistant Neisseria gonorrhoeae global estimates—impacts on doxycycline post-exposure prophylaxis implementation and monitoring: a systematic review

Kim Do , Magnus Unemo , Chris Kenyon , Jane S Hocking , Fabian Yuh Shiong Kong

JAC-Antimicrobial Resistance | 2025 Jul 9;7(4):dlaf120 | DOI: 10.1093/jacamr/dlaf120

A novel azithromycin resistance mutation in Mycoplasma genitalium induced in vitro

Teck-Phui Chua, Jennifer Danielewski, Catriona S Bradshaw, Dorothy A Machalek, Suzanne M Garland, Jose L Huaman, Jørgen S Jensen, Gerald L Murray

Journal of Antimicrobial Chemotherapy | 2025 Jul 1;80(7):2044-2050 | DOI: 10.1093/jac/dkaf174

Factors that contribute to the success of primary isolation of Mycoplasma genitalium from clinical samples

Jose L Huaman, Catriona S Bradshaw, Teck-Phui Chua, Erica L Plummer, Jennifer A Danielewski, Lenka A Vodstrcil, Jorgen S Jensen, Suzanne M Garland, Natasha Wild, Gerald L Murray

Journal of Medical Microbiology | 2025 Jul;74(7):002040 | DOI: 10.1099/jmm.0.002040

GBTQ+ safe sex entanglements: Finding the bacterial in the age of resistant STIs and prevention innovation

Shiva Chandra, Alex Broom, Damien Ridge, Katherine Kenny, Michelle Peterie, Jennifer Broom, Bridget Haire  Lise Lafferty, Carla Treloar, Stephanie Raymond, Catriona Bradshaw, Tanya Applegate, Rebecca Guy

Social Science & Medicine | 2025 May 9;379:118162 | DOI: 10.1016/j.socscimed.2025.118162 | Epub ahead of print

Oral gepotidacin for the treatment of uncomplicated urogenital gonorrhoea (EAGLE-1): a phase 3 randomised, open-label, non-inferiority, multicentre study

Jonathan D C Ross, Janet Wilson, Kimberly A Workowski, Stephanie N Taylor, David A Lewis, Sally Gatsi, William Flight, Nicole E Scangarella-Oman, Charles Jakielaszek, Dan Lythgoe, Marcy Powell, Salim Janmohamed, Judith Absalon, Caroline Perry

The Lancet | 2025 May 3;405(10489):1608-1620 | DOI: 10.1016/S0140-6736(25)00628-2

Diversity of Mycoplasma genitalium strains in Australia: relationship with sexual networks and antimicrobial resistance

Teck-Phui Chua, Jennifer A Danielewski, Emma L Sweeney, Erica L Plummer, Catriona S Bradshaw, David M Whiley, Dorothy A Machalek, Suzanne M Garland, Gerald L Murray

European Journal of Clinical Microbiology & Infectious Diseases | 2025 May;44(5):1167-1175 | DOI: 10.1007/s10096-025-05081-0

GS-1 blocks entry of herpes viruses and more broadly inhibits enveloped viruses

EA Monson, MG Lloyd, RI Johnson, K Caracciolo, J Whan, TF Rau, SL Londrigan, JF Moffat, AJ Mayfosh, KJ Helbig

Antiviral Research | 2025 May;237:106136 | DOI: 10.1016/j.antiviral.2025.106136

Evolving patterns of macrolide and fluoroquinolone resistance in Mycoplasma genitalium: an updated systematic review and meta-analysis

Teck-Phui Chua, Lenka A Vodstrcil, Gerald L Murray, Erica L Plummer, Jørgen S Jensen, Magnus Unemo, Eric P F Chow, Nicola Low, David M Whiley, Emma L Sweeney, Jane S Hocking, Jennifer A Danielewski, Suzanne M Garland, Christopher K Fairley, Lei Zhang, Catriona S Bradshaw, Dorothy A Machalek

The Lancet Microbe | 2025 Mar 24:101047 | DOI: 10.1016/j.lanmic.2024.101047 | Epub ahead of print

A Novel Ammonium Carboxylate Salt of Undecylenic Acid for the Topical Treatment of Gram-Positive and Antibiotic-Resistant Skin Infections

Alyce Mayfosh, Thomas Rau

Experimental Dermatology | 2025 Mar;34(3):e70075 | DOI: 10.1111/exd.70075

Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis

Lenka A Vodstrcil, Erica L Plummer, Christopher K Fairley, Jane S Hocking, Matthew G Law, Kathy Petoumenos, Deborah Bateson, Gerald L Murray, Basil Donovan, Eric P F Chow, Marcus Y Chen, John Kaldor, Catriona S Bradshaw; StepUp Team

The New England Journal of Medicine | 2025 March 6;392(10):947-957 | DOI: 10.1056/NEJMoa2405404

PathoGD: an integrative genomics approach to primer and guide RNA design for CRISPR-based diagnostics

Soo Jen Low, Matthew O’Neill, William J Kerry, Natasha Wild, Marcelina Krysiak, Yi Nong, Francesca Azzato, Eileen Hor, Lewis Williams, George Taiaroa, Eike Steinig, Shivani Pasricha & Deborah A Williamson

Communications Biology | 2025 January 30;8(1):147 | DOI: 10.1038/s42003-025-07591-1

Emerging Dilemmas in the Age of Resistance: The Case of Sexually Transmitted Infections

Shiva Chandra, Alex Broom, Michelle Peterie, Damien Ridge, Katherine Kenny, Lise Lafferty, Carla Treloar, Tanya Applegate, Jennifer Broom

Qualitative Health Research | 2024 December 16:10497323241302668 | DOI: 10.1177/10497323241302668

Longitudinal genomic analysis of Neisseria gonorrhoeae transmission dynamics in Australia

Mona L Taouk, George Taiaroa, Sebastian Duchene, Soo Jen Low, Charlie K Higgs, Darren Y J Lee, Shivani Pasricha, Nasra Higgins, Danielle J Ingle, Benjamin P Howden, Marcus Y Chen, Christopher K Fairley, Eric P F Chow & Deborah A Williamson

Nature Communications | 2024 September 14;15, Article number: 8076 (2024). | DOI: 10.1038/s41467-024-52343-0

Emergence of an extensively drug-resistant Neisseria gonorrhoeae clone

Sebastiaan J van Hal, Norelle Sherry, Geoff Coombs, Shakeel Mowlaboccus, David M Whiley, Monica M Lahra

The Lancet Infectious Diseases | 2024 August 7;24:00486-9. | DOI: 10.1016/S1473-3099(24)00486-9

A novel murine model mimicking male genital Neisseria species infection using Neisseria musculi

Emily R Bryan, Julia McRae, Vishnu Kumar, Logan K Trim, Toby I Maidment, Jacob A D Tickner, Emma L Sweeney, Elizabeth D Williams, David M Whiley, Kenneth W Beagley

Biology of Reproduction | 2024 July 8;ioae100. | DOI: 10.1093/biolre/ioae100

The AMR Hub: a public–private partnership to overcome barriers to commercialisation and deliver antimicrobial stewardship innovations

Michelle Bonello, Tanya L Applegate, Steve Badman, Catriona S Bradshaw, Alex Broom, Paul Field, Jane S Hocking, Wilhelmina M Huston, Fabian Kong, Gerald L Murray, Elisa Mokany, Shivani Pasricha, Alison V Todd, David M Whiley, Virginia Wiseman, and Rebecca Guy, on behalf of investigators and partner investigators of the AMR Hub

Microbiology Australia | 2024 May 23;45:48-53 | DOI: 10.1071/MA24017

Response to the ASHM 2023 statement on the use of doxy-PEP in Australia: considerations and recommendations

Sara F E Bell, Emma L Sweeney, Fabian Y S Kong, David M Whiley, Catriona S Bradshaw, Jacob A Tickner

The Medical Journal of Australia | 2024 Apr 15;220(7):356-360. | DOI: 10.5694/mja2.52255

ASHM Statement

STI pathogens in the oropharynx: update on screening and treatment

Eric P F Chow, Christopher K Fairley, Fabian Y S Kong

Current Opinion in Infectious Diseases | 2024 Feb 1;37(1):35-45 | DOI: 10.1097/QCO.0000000000000997

Concurrent parC and gyrA fluoroquinolone resistance mutations and associated strains in Mycoplasma genitalium in Queensland, Australia

Nicole G Ertl, Taylah K Anderson, Carolyn J Pardo, Toby I Maidment, Gerald L Murray, Catriona S Bradshaw, David M Whiley, Emma L Sweeney

Journal of Antimicrobial Chemotherapy | 2023 Dec 15:dkad373 | DOI: 10.1093/jac/dkad373

Sex, drugs and superbugs: The rise of drug resistant STIs

Alex Broom, Michelle Peterie, Damien Ridge, Lise Lafferty, Katherine Kenny, Jennifer Broom, Angela Kelly-Hanku, Carla Treloar, Tanya Applegate

SSM – Qualitative Research in Health | 2023 December;4:100310 | DOI: 10.1016/j.ssmqr.2023.100310

Evaluating preanalytical sample storage parameters for nucleic acid-based detection of Neisseria gonorrhoeae

Janath A Fernando, Marcelina Krysiak, Jacqueline Prestedge, Francesca Azzato, Deborah A Williamson, Shivani Pasricha

Sexually Transmitted Infections | 2023 Nov 24:sextrans-2023-055859 | DOI: 10.1136/sextrans-2023-055859

Efficacy of Sitafloxacin for Mycoplasma genitalium in an Era of Increasing Antimicrobial Resistance

Ranjit S Samra, Erica L Plummer, Lenka A Vodstrcil, Ivette Aguirre, Emily J Clarke, Christopher K Fairley, Eric P F Chow, Catriona S Bradshaw

Open Forum Infectious Diseases | 2023 Nov 22;10(12):ofad590 | DOI: 10.1093/ofid/ofad590

Economies of resistance

Michelle Peterie, Alex Broom, Katherine Kenny, Jennifer Broom, David Regan, Lise Lafferty, Angela Kelly-Hanku, Carla Treloar

Critical Public Health | Published online: 24 Oct 2023 | DOI: 10.1080/09581596.2023.2271140

Selection of Neisseria gonorrhoeae ceftriaxone resistance using doxycycline post-exposure prophylaxis

David M Whiley, Jacob A Tickner, Ratan L Kundu, Tiffany R Hogan, Sebastiaan J van Hal, Monica M Lahra

The Lancet Infectious Diseases | 2023 Aug;23(8):e268-e269 | DOI: 10.1016/S1473-3099(23)00359-6

Neisseria gonorrhoeae ciprofloxacin susceptibility testing and gyrA targets

Jacob A Tickner, Ella Trembizki, David M Whiley

The Lancet Microbe | 2023 Aug;4(8):e574 | DOI: 10.1016/S2666-5247(23)00149-0

Important considerations regarding the widespread use of doxycycline chemoprophylaxis against sexually transmitted infections

Fabian Y S Kong, Chris Kenyon, Magnus Unemo

Journal of Antimicrobial Chemotherapy | 2023 Jul 5;78(7):1561-1568 | DOI: 10.1093/jac/dkad129

Antimicrobial susceptibility assays for Neisseria gonorrhoeae: a proof-of-principle population-based retrospective analysis

Sara F E Bell, Robert S Ware, David A Lewis, Monica M Lahra, David M Whiley

The Lancet Microbe | 2023 Jul;4(7):e544-e551 | DOI: 10.1016/S2666-5247(23)00071-X

gyrA Mutations in Mycoplasma Genitalium and Their Contribution to Moxifloxacin Failure: Time for the Next Generation of Resistance-guided Therapy

Gerald L Murray, Erica L Plummer, Kaveesha Bodiyabadu, Lenka A Vodstrcil, Jose L Huaman, Jennifer A Danielewski, Teck Phui Chua, Dorothy A Machalek, Suzanne Garland, Michelle Doyle, Emma L Sweeney, David M Whiley, Catriona S Bradshaw

Clinical Infectious Diseases | 2023 Jun 16;76(12):2187-2195 | DOI: 10.1093/cid/ciad057

Quantitation of Mycoplasma genitalium using droplet digital PCR

Cheng Rui Peh, Jennifer Danielewski, Teck Phui Chua, Kaveesha Bodiyabadu, Dorothy A Machalek, Suzanne M Garland, Catriona S Bradshaw, Gerald L Murray

Letters in Applied Microbiology | 2023 Jun 1;76(6):ovad064 | DOI: 10.1093/lambio/ovad064

The Urethral Microbiota of Men with and without Idiopathic Urethritis

Erica L Plummer, Larissa K Ratten, Lenka A Vodstrcil, Gerald L Murray, Jennifer A Danielewski, Christopher K Fairley, Suzanne M Garland, Eric P F Chow, Catriona S Bradshaw

mBio | 2022 Oct 26;13(5):e0221322 | DOI: 10.1128/mbio.02213-22

Vulnerability and antimicrobial resistance

Alex Broom, Michelle Peterie, Katherine Kenny, Jennifer Broom, Angela Kelly-Hanku, Lise Lafferty, Carla Treloar, Tanya Applegate

Critical Public Health | 2022 Sep 22; 33(3):308-317 | DOI: 10.1080/09581596.2022.2123733

Combination therapy for Mycoplasma genitalium, and new insights into the utility of parC mutant detection to improve cure

Lenka A Vodstrcil, Erica L Plummer, Michelle Doyle, Gerald L Murray, Kaveesha Bodiyabadu, Jorgen S Jensen, David Whiley, Emma Sweeney, Deborah A Williamson, Eric P F Chow, Christopher K Fairley, Catriona S Bradshaw

Clinical Infectious Diseases | 2022 Sep 14;75(5):813-823 | DOI: 10.1093/cid/ciab1058

Individualised treatment of Mycoplasma genitalium infection – it is time to incorporate quinolone resistance testing into clinical care

Emma L Sweeney, Catriona S Bradshaw, Gerald L Murray, David M Whiley

The Lancet Infectious Diseases | 2022 Sep;22(9):e267-e270 | DOI: 10.1016/S1473-3099(21)00629-0

Mycoplasma genitalium: enhanced management using expanded individualised treatment strategies, Sex

Emma L Sweeney, David M Whiley, Gerald L Murray, Catriona S Bradshaw

Sexual Health | 2022 Aug;19(4):248-254 | DOI: 10.1071/SH22012

Novel probe-based melting curve assays for the characterisation of fluoroquinolone resistance in Mycoplasma genitalium

Jacob A Tickner, Catriona S Bradshaw, Gerald L Murray, David M Whiley, Emma L Sweeney

Journal of Antimicrobial Chemotherapy | 2022 May 29;77(6):1592-1599 | DOI: 10.1093/jac/dkac097

parC variants in Mycoplasma genitalium: trends over time and association with moxifloxacin failure

★ Editor’s Pick

Gerald L Murray, Kaveesha Bodiyabadu, Lenka A Vodstrcil, Dorothy A Machalek, Jennifer Danielewski, Erica L Plummer, Suzanne M Garland, David M Whiley, Emma L Sweeney, Catriona S Bradshaw

Antimicrobial Agents in Chemotherapy | 2022 May 17;66(5):e0027822 | DOI: 10.1128/aac.00278-22

Impact of 16S rRNA Single Nucleotide Polymorphisms on Mycoplasma genitalium Organism Load with Doxycycline Treatment

Teck-Phui Chua, Jennifer Danielewski, Kaveesha Bodiyabadu, Catriona S Bradshaw, Dorothy A Machalek, Suzanne M Garland, Erica L Plummer, Lenka A Vodstrcil, Gerald L Murray

Antimicrobial Agents and Chemotherapy | 2022 May 17;66(5):e0024322 | DOI: 10.1128/aac.00243-22