Output

Publications

 

 

Articles

Neisseria gonorrhoeae ciprofloxacin susceptibility testing and gyrA targets

Jacob A Tickner, Ella Trembizki, David M Whiley

Selection of Neisseria gonorrhoeae ceftriaxone resistance using doxycycline post-exposure prophylaxis

David M Whiley, Jacob A Tickner, Ratan L Kundu, Tiffany R Hogan, Sebastiaan J van Hal, Monica M Lahra.

The Urethral Microbiota of Men with and without Idiopathic Urethritis

Plummer EL, Ratten LK, Vodstrcil LA, Murray GL, Danielewski JA, Fairley CK, Garland SM, Chow EPF, Bradshaw CS. The Urethral Microbiota of Men with and without Idiopathic Urethritis. mBio. 2022 Oct 26;13(5):e0221322. doi: 10.1128/mbio.02213-22. Epub 2022 Oct 3. PMID: 36190130; PMCID: PMC9600694.

gyrA Mutations in Mycoplasma Genitalium and Their Contribution to Moxifloxacin Failure: Time for the Next Generation of Resistance-guided Therapy

Gerald L Murray and others, gyrA Mutations in Mycoplasma Genitalium and Their Contribution to Moxifloxacin Failure: Time for the Next Generation of Resistance-guided Therapy, Clinical Infectious Diseases, 2023;, ciad057, https://doi.org/10.1093/cid/ciad057

Vulnerability and antimicrobial resistance

Alex Broom, Michelle Peterie, Katherine Kenny, Jennifer Broom, Angela Kelly- Hanku, Lise Lafferty, Carla Treloar & Tanya Applegate (2022): Vulnerability and antimicrobial resistance, Critical Public Health, DOI: 10.1080/09581596.2022.2123733

Important considerations regarding the widespread use of doxycycline chemoprophylaxis against sexually transmitted infections

The antibiotic doxycycline can be used to prevent new STIs but we have some concerns, especially re antimicrobial resistance in gonorrhoea and commensals.

Fabian Yuh Shiong Kong, Chris Kenyon, Magnus Unemo, Important considerations regarding the widespread use of doxycycline chemoprophylaxis against sexually transmitted infections, Journal of Antimicrobial Chemotherapy, 2023;, dkad129

Impact of 16S rRNA Single Nucleotide Polymorphisms on Mycoplasma genitalium Organism Load with Doxycycline Treatment

Chua TP, Danielewski J, Bodiyabadu K, Bradshaw CS, Machalek DA, Garland SM, Plummer EL, Vodstrcil LA, Murray GL. Antimicrob Agents Chemother. 2022 Apr 14:e0024322. doi: 10.1128/aac.00243-22. Online ahead of print.PMID: 35420491

ParC variants in Mycoplasma genitalium: trends over time and association with moxifloxacin failure
★ Editor’s Pick

Murray GL, Bodiyabadu K, Vodstrcil LA, Machalek DA, Danielewski, J, Plummer, EL, Garland,SM, Whiley, DM, Sweeney, EL, Bradshaw CS. ParC variants in Mycoplasma genitalium: trends over time and association with moxifloxacin failure Journal of Antimicrobial Chemotherapy, Accepted April 2022.

Mycoplasma genitalium: enhanced management using expanded individualised treatment strategies, Sex Health

Sweeney EL, Whiley DM, Murray GL, Bradshaw CS. Mycoplasma genitalium: enhanced management using expanded individualised treatment strategies, Sex Health. Invited Review Sex Health Accepted March, 2022

Novel probe-based melting curve assays for the characterisation of fluoroquinolone resistance in Mycoplasma genitalium

Tickner JA, Bradshaw CS, Murray GL, Whiley DM Sweeney EL. Novel probe-based melting curve assays for the characterisation of fluoroquinolone resistance in Mycoplasma genitalium. Antimicrobial Agents and Chemotherapy Accepted Feb, 2022

Combination therapy for Mycoplasma genitalium, and new insights into the utility of parC mutant detection to improve cure

Vodstrcil LA, Plummer EL, Doyle M, Murray GL, Bodiyabadu K,  Jensen JS, Whiley DM, Sweeney EL, Williamson DA, Chow EPF, Fairley CK, Bradshaw CS. Combination therapy for Mycoplasma genitalium, and new insights into the utility of parC mutant detection to improve cure. Clin Infect Dis Jan 4 2022.

Individualised treatment of Mycoplasma genitalium infection – it is time to incorporate quinolone resistance testing into clinical care

Sweeney EL, Bradshaw CS, Murray GL & Whiley DM Individualised treatment of Mycoplasma genitalium infection – it is time to incorporate quinolone resistance testing into clinical care. Lancet Infect Dis Accepted Sept 2021